UTI w/ Antibiotic Resistance

Molecular microbiology identifies microorganisms including bacteria, fungi and viruses through DNA detection. This technique is very sensitive, specific, and rapid compared to traditional microbiology procedures, creating a powerful diagnostic tool for physicians.

Our profile delivers a snapshot of a patient’s urinary tract micro-environment covering 35 organisms. Meridian’s scientific team utilizes
cutting-edge technology to detect pathogenic and nonpathogenic bacterial species. Additionally, the test also defines the genes associated with antibiotic resistance.

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UTI w/ Antibiotic Resistance

UTIs account for more than 8 million healthcare visits and 100,000 hospitalizations each year. Overall expenditures for UTIs in the U.S. are estimated to be $3.4 billion. Much of this is due to the slow turn around time of the traditional culture and the fact that it misses up to two-thirds of all positive UTIs.

Acinetobacter baumanii Gardnerella vaginalis Pseudomonas aeruginosa
Bacillus atrophaeus Haemophilus influenzae Pseudomonas aeruginosa
Candida albicans Herpes Simplex virus 1 & 2 Serratia marcescens
Candida glabrata Klebsiella oxytoca Staphylococcus aureus
Chlamydia trachomatis Klebsiella pneumoniae Staphylococcus epidermidis
Citrobacter freundii Megasphaera 1 Streptococcus agalactiae
Citrobacter koseri Morganella morganii Streptococcus pyogenes
Enterobacter aerogenes Mycoplasma genitalium Treponema pallidum
Enterobacter cloacae Mycoplasma hominis Trichomonas vaginalis
Enterococcus faecalis Neisseria gonorrhea Ureaplasma parvum
Enterococcus faecium Proteus mirabilis Ureaplasma urealyticum
Escherichia coli Proteus vulgaris

Antibiotic resistance can be identified for the following classes of antibiotics:

Antibiotic Resistance Gene Affected Antibiotic Class
blaNDM, CTX-M-Grp 1 Extended- Spectrum- Betalactamase
aac(6’)-lb-cr/aac(6’)-lb-cr4 Aminoglycoside Resistance
mecA Beta-lactams and Methicillin Resistance
blaKPC Klebsiella pneumoniae Carbapenase
vanC Glycopeptide (vancomycin) Resistance
ermB Macrolide Resistance
ampC Cephalosporin Resistance
tetM Tetracycline Resistance
qnrS Quinolone and Fluroquinolone Resistance

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