Pharmacogenomics (PGx)
Pharmacogenetics is the relationship between a patient’s unique genetic makeup and their response to certain medications. Genetic mutations can cause either higher or lower rates of metabolism for known drugs.
Testing will specify how quickly your body metabolizes, or filters, any given drug. Some patients are rapid metabolizers, flushing medication so quickly from their system that their body does not benefit from the medication. Poor metabolizers, on the other hand, can be harmed because the normal dose of medicine is too much for their body to metabolize. This test provides a physician vital information that is needed when prescribing medication. This means the right drug for the right patient at the right dose, ultimately optimizing the patients drug therapy outcome.

Pharmacogenetic Test Summary
Test Summary | ||
---|---|---|
ANKK1/DRD2 | DRD2:Taq1A G/G | Unaltered DRD2 function |
Apolipoprotein E |
ε3/ε3 | Normal APOE function |
COMT | Val158Met G/G | High/Normal COMT Activity |
CYP1A2 | *1A/*1L | Normal Metabolizer- Possible |
CYP2B6 | *1/*6 | Intermediate Metabolizer |
CYP2C19 | *17/*17 | Ultra-Rapid Metabolizer |
CYP2C9 | *1/*1 | Normal Metabolizer |
CYP2D6 | *10/*17 | Intermediate Metabolizer |
CYP3A4 | *1/*1B | Normal Metabolizer |
CYP3A5 | *3/*6 | Poor Metabolizer |
Factor II | rs1799963 GG | Normal Thrombosis Risk |
Factor V | Leiden rs6025 CC | Normal Thrombosis Risk |
ITGB3 | 176T>C T/T | Normal Platelet Reactivity |
LPA | rs10455872 A/A | Wild-type for rs10455872 |
LPA | rs3798220 T/T | Wild-type for rs3798220 |
MTHFR | c.665C>T GG | Normal MTHFR Activity |
MTHFR | c.1286A>C GT | Reduced MTHFR Activity |
OPRM1 | A118G A/A | Normal OPRM1 Function |
SLCO1B1 | 521T>C T/T | Normal Function |
TPMT | *1/*1 | Normal Metabolizer |
VKORC1 | -1639G>A G/G | Low Warfarin Sensitivity |